A new study has found that a daily dose of aspirin or NSAIDs can massively reduce the risk of a common form of cancer.

Colorectal cancer is a particularly common type of cancer, and aspirin may cut the risk by up to 45 percent, according to a Los Angeles Times report.

People who take a daily dose of aspirin every day for at least five years were 27 percent less likely to get diagnosed with colorectal cancer when they took 75 to 150 milligrams. And for people who took nonsteroidal anti-inflammatory drugs (NSAIDs), the results were even more pronounced: NSAIDs taken over five years caused people to have a 30 to 45 percent lower risk than those who didn’t take anything. NSAIDs include painkillers like ibuprofen, which is found in medications like Advil and Motrin.

The findings were published in the Annals of Internal Medicine.

It’s not the first time studies have indicated that aspirin or NSAIDs can help protect against colorectal cancer, but they didn’t examine the proper dose and how long it should be taken.

Researchers used data from Denmark, which examined 10,280 adults who had been diagnosed with colorectal cancer between 1994 and 201. They used 10 controls for each patient — people who don’t have cancer but were born in the same year and were of the same gender.

The researchers also used national databases to determine the drugs they took.

The findings indicated that the drugs were extremely effective at preventing cancer, as long as people took it for five years or more.

To get the benefits, the patients had to take a fairly high dose — about three times higher than the median dose.

The findings held even when controlling for factors like diet, alcohol use, and weight.